Deathclaws here will get through the top two floors with ease, start to die on the 3rd floor, and be finished off on the fourth floor. In my not so fancy vault with 100 dwellers, everyone on the top floors is carrying rifles or better (so minimum 5 damage per hit on most of the second floor and third floor, min 6 damage on the topmost floor). No one dies when this vault is attacked, but they whine about the damage they took. In that vault, everyone on the top floors is carrying weapons that do 10+ damage per hit, and the deathclaws still get past vault entrance, top floor room (with 6 dwellers), and one or both of the second floor rooms before dying. In my fancy vault with 150+ dwellers and Mr Handys, the deathclaws will be killed on the second or third level down. You can try sending the defensive guys a few rooms ahead of the deathclaws to wait for them, but equipping the the dwellers assigned to the room with guns is faster and should have better results.

The deathclaws move from room to room fairly quickly, so manually sending a dweller with the best guns to chase them down is difficult. Your goal is to have each room wear the deathclaws down as they go deeper into the vault. Posting guards in the vault entrance is also helpful.

You can minimize the damage that the deathclaws cause by arming all of the dwellers in the topmost levels with the best weapons and outfits you have. I haven't done testing to determine if there is a lower percentage chance for lunchbox dwellers, but I have triggered a deathclaw attack when I brought Bittercup into the vault. Dwellers from lunchboxes don't bring deathclaw attacks when they join the waiting line, but they can still trigger an attack when they enter the vault. In case you thought lunchboxes would be your savior: sorry. Obviously this is not really feasible as it prevents you from adding fresh blood to your vault and from getting the weapons you need to defend it. You can stop them from coming by not clicking on the radio room (so no one gets added to the line outside the vault) and by never letting dwellers in or out of the vault (so the door never opens). How can I stop all these deathclaws from eating my dwellers, while still attracting new ones? You can't stop them They don't seem to attack randomly while nothing else is going on. I've noticed that deathclaws tend to attack right after a new dweller joins the waiting line outside my vault OR right after I let someone into the vault from the waiting line.

Fallout shelter room size efficiency